| S.No. |
Product |
Drug Internediate for
(Name of the Drug) |
Application & other remarks
|
| 1. |
N-(2-Hydroxyethyl)
Morpholine (HEM) or
Morpholinoethanol
CAS No.622-40-2
|
a) Mycophenolate Mofetil
b) Morniflumaate
c) Pinaverium Bromide
|
a) Imminosuppressive agent
b) Antipyretic & anti-inflamatory
agent, Bank-pain treatment
Muscle relaxant
c) Antispasmodic & when HEM
is reacted with Thionyl Chloride,
N(2-Chloroethyl) Morpholine,
HCI is formed which is a drug
Intermediate for Nimorazone,
Floredil, Pholcodine, Morniamide.
|
| 2. |
N-(2-Hydroxyethyl)
Piperidine or 2-Piperidi-
noethanol (2-PIPEtOH)
CAS No.3040-44-6
|
a) Flavoxate
Hydrochloride
b) Raloxifene
Hydrochloride
|
a) Antispasmodic & in treatment of
urinary incontinence
b) Antisteoporotic & when 2-PIPEtOH
is reacted with Thionyl Chloride,
N-(2Chloroethyl) Piperidine
Hydrochloride is formed, which is
a drug intermediate for Picoperine,
Tiquizium Bromide, Fenpiverinium Bromide.
|
| 3. |
N-(2-Hydroxyethyl)
Pyrrolidine or
Epolamine or 2-
Pyrrolidinoethanol
|
Centchroman (Ormeloxifene)
|
Oral Contraceptive & Epolamine is
reacted with Thionyl Chloride,
N-(2-Chloroethyl) Pyrrolidine
Hydrochloride is formed, which is
|
| 4. |
N-Methyl Morpholine
(NMM)
CAS No.109-02-4
|
a) Nazasetron (Azasetron)
b) Temocapril
c) Tiemonium Iodide
d) Cephalexin Monohydrate
(Penicillin G Route)
|
a) Antiemetic
b) Antibacterial
c) Antispasmodic
Also, used as solvent in 'peptide'
preparation and many other
products
|
| 5. |
N-Benzylethanolamine
(N-BzEA) CAS No.104-63-2
|
Phenmetrazine |
Central Nervous Stimulant |
| 6. |
Ethylmonoethanolamine
(EMEA) CAS No.110-73-6
|
Bamifylline |
Bronchodilator |
| 7. |
Monoethanolamine (MEA)
CAS No.141-43-5
|
Amlodipine |
Antianginal, Antihypertensive |
| 8. |
N-Ethyl Morpholine (NEM)
CAS No.100-74-3
|
Meclofenamic acid |
For Joint Muscular pain, Arthritis |
| 9. |
Dimethyl Ethanolamine or
Deanol CAS No.108-01-0
|
Deaner
(Pabenol, Diforene)
|
Antidepressant |
| 10. |
2-Phenoxyethanol,
CAS No.122-99-6
|
In many Pharma products |
Antimicrobial preservative. Also used
topically in treatment of bacterial
infection
|
| 11. |
Methylmonoethanolamine
(MMEA) CAS No.109-83-1
|
Betahistine & its dihydro-
chloride (Betaserc or Serc
or Vasomotal)
|
Vasolidator |
| 12. |
Dimethyl Ethanolamine |
Novaldiamine |
Anti-Malarial drug |
